FOXM1 and acute lymphoblastic leukemia: As Foxm1 is a critical regulator of oxidative responses6, we analysed the intracellular reactive oxygen species (ROS) formation in the presence and absence of Foxm1 in BCR-ABL1-transformed ALL cells and observed consistently higher ROS levels after Foxm1 deletion (Fig. 5a) but not in Cre-transduced Foxm1+/+ cells (Supplementary Fig. 5a).