To investigate a potential role of FOXM1 in transformed B cells, we used a mouse model for Ph+ ALL: to this end, BM-derived B-cell precursors were cultured in the presence of IL-7 and transformed with a retroviral BCR-ABL1 expression vector (schematic shown in Supplementary Fig. 3a). The gene discussed is ABL1; the disease is acute lymphoblastic leukemia.