Interestingly, STAT3 is activated in ALS patients and SOD1G93A mice (Shibata et al., 2009, 2010), thus we determined whether OXR1 overexpression alters levels of phosphorylated STAT3 (p-STAT3) at Day 90 by immunoblotting. This evidence concerns the gene OXR1 and amyotrophic lateral sclerosis.