In the present studies, we investigated the effect of TPD7 (N-(4′-acetyl-3′,5,6-trimethoxybiphenyl-3-yl)-N′-[4-(3-morpholin-4-ylpropoxy)phenyl]urea) as a novel regulator of CXCR4 expression and function in breast cancer. Here, CXCR4 is linked to breast carcinoma.