Despite a recent pooled analysis of prospective studies reported that high adherence to this dietary pattern was associated with a reduced risk of developing type 2 diabetes [30], it is noteworthy that all the aforementioned studies conducted in non-Mediterranean countries, as well as others specifically focused on diabetes still in multiethnic population [31] did not report benefits of high adherence to a Mediterranean-type diet on glucose and insulin metabolism. Here, INS is linked to type 2 diabetes mellitus.