Furthermore, real-time PCR results of Dicer and PKC-α expression in clinical BC samples showed that the both proteins were produced more in the high-grade papillary urothelial carcinoma (HGPUC) than in the low-grade papillary urothelial carcinoma (LGPUC; Dicer: <0.01, PKC-α: <0.01)or in the normal urothelium (Dicer: <0.01, PKC-α: <0.01). This evidence concerns the gene PRKCA and breast cancer.