While the exact mechanisms by which these fetal genes affect cardiac functions are not well-understood, comparative studies in the coexpression networks of cardiac genes in the fetal (developing) myocardium, failing myocardium and cardiac hypertrophy, identified MYH6, MYH7 and SERCA to be the most critical fetal genes to be expressed in fetal heart and diseased tissues [10]. Here, MYH6 is linked to cardiac hypertrophy.