Thus, after adjusting for potential confounding factors, the increased risk of relapse (pooled hazard ratios based on random-effects meta-analysis) for patients with increased levels of ABCA1, ACSL1, AGPAT1 or SCD was of HR (95% CI): 3.78 (2.03–7.03), p < 0.001; HR (95% CI): 3.14 (1.61–6.13), p < 0.001; HR (95% CI): 3.65 (1.93–6.91), p < 0.001; and HR (95% CI): 2.81 (1.46–5.38), p = 0.002 respectively. This evidence concerns the gene ACSL1 and Schnyder corneal dystrophy.