In addition, reported data suggest that ABCA1 gene might contribute to a more aggressive growth of multiple drug resistant melanomas [21], and the individual association of ABCA1 with a more aggressive phenotype of colorectal tumors has been also identified in an additional study focused on the relationship between metabolic syndrome and colorectal cancer (Vargas T et al., 2014) [22]. This evidence concerns the gene ABCA1 and colorectal neoplasm.