KLK3 and neoplasm: The predictive accuracy of established predictors of BR yielded similar results; at 48 months, the AUC was 0.68 (95% CI, 0.57–0.78) for tumor stage, 0.67 (95% CI, 0.58-0.76) for Gleason score, 0.63 (95% CI, 0.54–0.73) for surgical margin status and 0.57 (95% CI, 46–69) for PSA level at diagnosis (Supplementary Fig. S4).