Using RT-PCR, we confirmed the down-regulation of four putative bivalent tumor suppressor genes, SLC17A7 [Solute carrier family 17, member 7] and SLC8A2 [Solute carrier family 8, member 2] (Figure 5A–5B), in an independent panel of GBM tissues compared with a panel of normal brain tissues in our laboratory. Here, SLC8A2 is linked to glioblastoma.