At 8h post-infection, a dose-dependent reduction in the VP0 and VP2 was observed in EV71-infected cells pre-treated with MINK siRNA (Fig. 3E panel i and 3F) as opposed to the constant protein expression level of VP0 and VP2 in cells treated with scrambled MINK siRNA (Fig. 3E panel ii and 3F). This evidence concerns the gene MINK1 and infection.