Compared to HF patients, hypertensive patients with dyspnea had significantly lower values of CT-1, syndecan, NT-proBNP, CysC, TGF beta and NGAL (p < 0.0001; p = 0.0015; p < 0.0001; p = 0.0001; p < 0.0001 and p = 0.036 respectively). This evidence concerns the gene NPPB and hydrops fetalis.