Although interscapular BAT weight was not different between WT and CD47-/- mice under either LF or HF feeding conditions (Fig. 1E), histology showed a decrease in intracellular lipid droplet size in BAT of HF-fed CD47 deficient mice compared to HF-fed WT mice, reflected by a decrease in relative lipid area (Fig. 8B, C). Here, CD47 is linked to hydrops fetalis.