SLC7A11 and primary effusion lymphoma: We also failed to detect xCT mRNA in human CD19+ primary B cells isolated from fresh peripheral blood mononuclear cells (PBMCs), which is paradoxical given that the virus is etiologically linked to two B cell lymphoproliferative disorders, namely multicentric Castleman’s disease (MCD) and primary effusion lymphoma (PEL; Cesarman et al., 1995; Soulier et al., 1995).