Targeting S100A7 may exploit its relationship with NF-κB because NF-κB target genes include transcription factors for a number of growth factors such as vascular endothelial growth factor, fibroblast growth factor, and platelet-derived growth factor, which have been linked to promoting cancer cell growth, tumor stroma development, and angiogenesis [27-29]. This evidence concerns the gene VEGFA and neoplasm.