CD133 and CD24, markers found in MM cells and glomerular progenitor cells28, 29, were expressed on almost all the cells at any differentiation time considered (Fig. 1d) however, their distribution changed from a punctuated staining in undifferentiated iPSCs to a characteristic well-organized peripheral pattern by day 12 (Fig. 1d). The gene discussed is PROM1; the disease is Miyoshi myopathy.