Because little is known on the association between RAD51-172G/T and XRCC2-41657C/T polymorphisms and TNBC, it was studied whether the polymorphisms in the two genes, being involved in the homologous recombination of double-strand breaks, could have been linked with the risk for triple-negative breast cancer in that Polish population. Here, XRCC2 is linked to triple-negative breast carcinoma.