Considering this along with our results on the expressional changes induced TGF-β1 and cancer cell conditioned/activated medium in BECs and HUVECs, the endothelial cell response enabling cancer cell TEM can be termed an endothelial-mesenchymal transition, EndMT being a prerequisite for metastatic extravasation and TEM. This evidence concerns the gene TGFB1 and cancer.