Tumour development was identical in C57BL/6 and 11c.OVA mice (MST 17 vs 15 days; p>0.05, Fig. 4C vs 4B) suggesting that, in the absence of OT-I Tcm-phenotype cell transfer, endogenous OVA-specific immunity which would differ between OVA-tolerant 11c.OVA and non-Tg mice, or other immune mechanisms was playing little role in tumour clearance. The gene discussed is OXT; the disease is neoplasm.