Depletion of DAPK2, when compared with the siNS control, led to clear phosphorylation/activation of ERK1/2Thr202/Tyr204 and JNKThr183/Tyr185 in U2OS and A549 cells, whereas phosphorylation of p38Thr180/Tyr182 was only observed in U2OS cells but not in A549 lung cancer cells (Figure 1aversusFigure 1e). Here, MAPK3 is linked to lung cancer.