We previously described that TIA1 and/or TIAR protein expression is decreased in a subset of human epithelial tumors.21 To evaluate a possible role for TIA proteins in human tumorigenesis, we analyzed TIA1 and TIAR expression in a cohort of patients with non-small-cell lung carcinoma (NSCLC). Here, TIAL1 is linked to non-small cell lung carcinoma.