CD79A and neoplasm: We can speculate that these patients come to medical attention for skeletal complications and require RT more frequently than patients with secretory MM, because the latter have useful tumor markers that may detect progressive disease at an earlier stage, or because they may present with MM manifestations that do not require RT, such as hyperviscosity syndrome due to IgG or IgA paraproteins, or cast nephropathy due to free light chain secretion (26).