APOE E 4 is associated with increased serum triglyceride (TG), TC and LDL-C levels [41], and the diseases with known or proposed association with oxidative stress and a proinflammatory status, for example, coronary heart disease and stroke [42], Alzheimer's disease [43], and psoriasis [44]. The gene discussed is APOE; the disease is early-onset autosomal dominant Alzheimer disease.