FOXO3 and Crohn disease: For example, a recent paper in Cell, leveraging from a GWAS on susceptibility, identified a non-coding polymorphism in FOXO3A not identified by the GWAS (rs12212067: T>G) that associated with the course of, but not susceptibility to, Crohn’s disease and rheumatoid arthritis, and with an increased risk of severe malaria39.