This current study is a derivation study to identify signs and symptoms that, combined with point of care heart-type fatty acid-binding protein (PoC H-FABP) testing, can be part of an algorithm to confirm or rule out ACS (meaning AMI and unstable angina (UA)) and AMI alone in a population of patients with complaints possibly due to myocardial ischaemia in general practice. This evidence concerns the gene FABP3 and angina pectoris.