MTOR and cancer: Among all the clusters identified in DEGs and ProgGenes, metabolism related cluster D1, replication and repair cluster D2, cell growth and death cluster D3, carbohydrate metabolism cluster P1, mTOR signaling cluster P2, cancer related cluster P5 were significant (p<0.05) or showed a tendency (p<0.1) for prognostic value for HCC, evaluated by both LOOCV and hierarchical clustering.