TNF and myeloid sarcoma: In monocytes, separated from blood samples from 11 untreated and 14 IFN-β treated MS patients (sub-study 2 population), we measured mRNA expression levels of the pro-inflammatory molecules IL12A, IL1B, IL23, IL6 and TNF (Fig. 3A) and the immunoregulatory molecules IL10, IL27 and EBI3 (Fig. 3B).