VHL and cancer: Several cancer-related genes PIK3CA, EVI1, SOX2, ETV5, ARNT, SETDB1, APH1A, CHD1L, PRKCI and ELK4 were located within the recurrently gained regions, while the VHL, XPC, MLH1, CTNNB1, FOXP1, STK11 and PTPN13 genes were located within the recurrently deleted regions.