According to the results of western blot, the gastric cancer and intestinal metaplasia with atypical hyperplasia groups were classified as the TRAF1, 4-1BB, and Bcl-xL high expression group, while the gastritis and atrophic gastritis groups were classified as the TRAF1, 4-1BB, and Bcl-xL low expression group. The gene discussed is TRAF1; the disease is gastric cancer.