POMC and adenoma: Moreover, it should be mentioned that we had the opportunity to observe that In1-19 treatment was able to exert a clear inhibition in the apoptotic rate in one ACTH-oma sample included in the study which, together with the previous results observed in GH-omas and ACTH-omas, further support the notion that treatment with the In1-ghrelin peptides influences multiple, clinically relevant parameters on human pituitary adenomas, and may thus offer the possibility of identifying new therapeutic tools to treat these adenomas.