Moreover, it should be mentioned that we had the opportunity to observe that In1-19 treatment was able to exert a clear inhibition in the apoptotic rate in one ACTH-oma sample included in the study which, together with the previous results observed in GH-omas and ACTH-omas, further support the notion that treatment with the In1-ghrelin peptides influences multiple, clinically relevant parameters on human pituitary adenomas, and may thus offer the possibility of identifying new therapeutic tools to treat these adenomas. The gene discussed is GH1; the disease is adenoma.