Methylation of SST was associated with several clinicopathologic factors, including tumor size (P = 0.043), stage (P = 0.008), GALR2 methylation (P = 0.041), TAC1 methylation (P = 0.040), and DAPK methylation (P = 0.012) (Table 1and S1 Table). Here, TAC1 is linked to neoplasm.