We started analysing thirteen WNT signaling genes that are known to have important function in leukemia, i.e., sFRP1, sFRP2, sFRP4, DKK1, DKK3, APC, APC2, RUNX1, WIF1, TCF1, LEF1, LKB1/STK11, and CTNNB1, and could confirm on our data that LEF1 [13], SFRP2 [6], RUNX1 [14], and AXIN2 have prognostic value. The gene discussed is LEF1; the disease is leukemia.