Although Yu et al.20 reported that overexpression of MUC5 genes is associated with early post-operative metastasis in NSCLC, they did not study the detailed relationships between MUC5B expression and clinicopathological features such as tumor differentiation and p-TNM stage with a large number of NSCLC cases. The gene discussed is MUC5B; the disease is non-small cell lung carcinoma.