MAPT and Alzheimer disease: In a study that compared different predictors using the Alzheimer ́s Disease Neuroimaging Initiative data, researchers found that fluorodeoxyglucose-positron emission tomography (FDG PET) and episodic memory performance were the strongest predictors of progression from MCI to AD, whereas CSF tau and Aβ combined with FDG-PET were predictive of cognitive decline onset [24].