AKT1 and cancer: Other human cancer cell lines affected by mistletoe lectins include acute lymphoblastic leukemia cells (NALM-6), glioblastoma cells through NK-mediated cell lysis, hepatoma carcinoma cells through a p53- and p21-independent mitochondrial controlled pathway, peripheral blood mononuclear cells via enhanced pro-apoptotic proteins, monocytic tumour cell lines via activating expression of individual interleukin mRNA, and epidermoid carcinoma cells (A253) by inducing dephosphorylation of Akt [31,32].