We also detected an early structural rearrangement, a 1,058 bp deletion in exon5 of MLLT3, a gene that is often translocated in leukemias (Additional file 2: Table S3), and early copy number changes, including a gain of chromosome 1q and loss of 1p, amplification of chromosome 8q (MYC) and loss of 17p. This evidence concerns the gene MLLT3 and leukemia.