ERBB2 and cancer: Currently, a broad range of different cancer target antigens is under clinical investigation in several clinical CAR T cell trials such as CD20, CD30, CD138, c-Met, EGFRvIII, FAB, GD2, HER2, WT1, PSMA, NY-ESO1, and others as reviewed in Corrigan-Curay et al. (2014) and Maus et al. (2014) and even more target antigens are under pre-clinical development (Kenderian et al., 2014; Leuci et al., 2014).