Finally, re-evaluation by functional annotation clustering of downregulated genes in GNE myopathy (Eisenberg et al., 2008) with the DAVID bioinformatics resources revealed slightly reduced expression of nuclear or steroid hormone receptors including hepatocyte nuclear factor 4-gamma (HNF4G), nuclear receptor subfamily 1, group I, member 3 (NR1I3), and nuclear receptor subfamily 1, group H, member 2 (NR1H2). Here, NR1I3 is linked to Distal myopathy, Nonaka type.