FMR1 and fragile X syndrome: More and more potential FMRP mRNA targets and interacting proteins have been identified in the mammalian brain, supporting the critical roles of FMRP in neurodevelopment, synaptic plasticity and other neurological disorders apart from fragile X syndrome (Wang et al., 2008b, 2012; Pasciuto and Bagni, 2014a; Suhl et al., 2014).