Ad-TRAIL-2A-HN had the strongest inhibitory effect (P < 0.01); Ad-TRAIL had a stable inhibitory effect that was weaker than that of the other viruses (P < 0.01), and Ad-HN showed a moderate inhibitory effect that showed large variation over the duration of the infection (1–7 days) (P > 0.05). This evidence concerns the gene TNFSF10 and infection.