However, two studies have now reported beneficial actions of the GLP-1 analogues, AC3174 and exendin-4, on post-MI survival and cardiac structure/function in rodent models, when administered from 2 days and 2 weeks after coronary artery ligation, respectively [21, 23], although another study failed to demonstrate equivalent beneficial effects when liraglutide was given 7 days post-MI [24]. This evidence concerns the gene GLP1R and myocardial infarction.