Soluble BCMA is elevated in the serum of MM patients,72 and successful donor lymphocyte infusion is associated with the formation of antibodies targeting BCMA.49 These observations, along with the ubiquitous yet selective expression of BCMA on MMCs, provide a strong rationale for the development of mAbs targeting BCMA. Here, TNFRSF17 is linked to Miyoshi myopathy.