In order to understand how regulation of this pathway affects the production of sAPPβ we generated two different views of the “Maturity onset diabetes of the young” pathway, one that demonstrated how individual proteins in this pathway regulate APP processing (Figs. 4A-D) and the other that consisted of proteins from this pathway as well as the “AD pathway” (Figs. 4A-D), with the aim of determining whether proteins in the diabetes pathway would interact with/regulate proteins that have been implicated in AD. This evidence concerns the gene APP and diabetes mellitus.