While both H1 and H2 receptors were constitutively expressed by EPC2-hTERT (Fig. 4A), non-EoE control (n = 8) (Fig. 4B), and EoE (n = 13) (Fig. 4C) cell lines, neither H3R nor H4R were detected in any of the studied cells (data not shown). This evidence concerns the gene HRH3 and eosinophilic esophagitis.