ELF3 and neoplasm: A recent report by Nakanishi et al. using a compound mouse line (Dclk1-Cre-ERT;Apcmin/+) confirmed that Dclk1 selectively marks tumor stem cells in the ApcMin/+ mice, and ablation of Dclk1+ cells results in a marked regression of polyps without apparent damage to the normal mouse intestine [23].