In the OMA group, we have identified four new polymorphisms: rs4703908, rs227849, rs966674, and rs2479037, with robust ORs. Rs2479037 is close to VTI1A, possibly involved in colorectal adenocarcinoma [40]. Rs4703908, associated with both OMA and intestinal DIE, is located near ZNF366 that plays an important role in regulating the expression of target genes in response to estrogen [41]. ZNF366 could be an independent prognostic factor for breast tumors [42]. Here, VTI1A is linked to colorectal adenocarcinoma.