A significant main effect of COMT met alleles (β = −32.5, SE 14.1, P = 0.0212) was qualified by COMT met alleles × conscientiousness (β = 0.73, SE 0.3, P = 0.0042) and COMT met alleles × anxiety interactions (β = −0.42, SE 0.16, P = 0.0078) (Table 4). This evidence concerns the gene COMT and Anxiety.