Increased cell proliferation in the SVZ and ectopic migration of neuroblasts have been observed in the striatum of MCAO-induced ischemic stroke models [41,42,43,44], and also after brain hemorrhage caused by injection of bacterial collagenase or blood [45,46,47], as well as in acute models of Parkinson’s Disease (PD) after administration of epidermal growth factor (EGF) and fibroblast growth factor 2 (FGF2) [48], and, moreover, after application of Noggin and brain-derived neurotrophic factor (BDNF) in adult rats [49]. This evidence concerns the gene EGF and Parkinson disease.