TDP-43 and FUS mutations are found in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) (Li et al., 2013), and mutations in hnRNPA1 and hnRPNPA2/B1 have also been found in ALS (Kim et al., 2013). Here, TARDBP is linked to amyotrophic lateral sclerosis.