Our data build on those of others showing that JNK, aPKC and Yki are key players in fly neoplasia (Leong et al., 2009; Grzeschik et al., 2010; Robinson et al., 2010; Zhu et al., 2010; Doggett et al., 2011; Sun and Irvine, 2011; Verghese et al., 2012). The gene discussed is MAPK8; the disease is neoplasm.