Prognostic factors including tumor differentiation, nerve infiltration, expression of GLUT1 in tumor, GOT1 in tumor, expression of LC3 in tumor, expression of BNIP3 in tumor, glucose-dependent metabolism, glutamine-dependent metabolism, categories of metabolism and numbers of metabolism types in tumor were analyzed in Multivariate models using Cox proportional hazards analysis. This evidence concerns the gene BNIP3 and neoplasm.