GLUD1 and familial pancreatic carcinoma: Recent evidence showed that pancreatic cancer cells mostly utilizes glutamic-oxaloacetic transaminase (including GOT1) (Non-canonical type) other than glutamate dehydrogenase (GLUD1) (Canonical type) for converting into alpha-ketoglutarate to fuel TCA cycle, which is obviously different from other kinds of tumors and normal cells.